Scientists finally crack nature’s most common chemical bond | College of Chemistry (berkeley.edu)
Illustration: A catalyst (center) based on iridium (blue ball) can snip a hydrogen atom (white balls) off a terminal methyl group (upper and lower left) to add a boron-oxygen compound (pink and red) that is easily swapped out for more complicated chemical groups. The reaction works on simple hydrocarbon chains (top reaction) or more complicated carbon compounds (bottom reaction). The exquisite selectivity of this catalytic reaction is due to the methyl group (yellow) that has been added to the iridium catalyst. The black balls are carbon atoms; red is oxygen; pink is boron. UC Berkeley image by John Hartwig.
The most common chemical bond in the living world — that between carbon and hydrogen — has long resisted attempts by chemists to crack it open, thwarting efforts to add new bells and whistles to old carbon-based molecules.